Difference between revisions of "Team:NAU-CHINA/Human Practices"

 
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        <p class="top-title">HUMAN PRACTICES</p>
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        <p class="sec-title">Overview</p>
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    <a href="https://2018.igem.org/Team:NAU-CHINA/IntegratedHP">
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            <p>As a “bigger picture” of iGEM, with the highest ideal to apply synthetic biology to benefit the world, the year-long human practice of our team goes along with our project. Through human practice, on one hand, we establish and improve our project, and apply our project to the real world; on the other hand, we bring scientific knowledge to the general public, educate teenagers and inspire students. Through human practice, we understand the relationship between the world and synthetic biology.</p> 
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<h1> Sliver</h1>
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<p>To establish an element with the function of analog-to-digital converter, our project can be used not only in EGFR targeted cancer monitoring and treatment, but also in other disease treatment, environmental pollution monitoring, and any other occasions which involve monitoring and “ all or nothing” corresponding.</p>
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<p>We thought carefully about what we can do to serve the world when we established our project. Based on plenty of research on the hottest issues, Human practice group of our team locked CAR-T, a kind of cancer immunotherapy. We intend to focus on Cytokine storm, a side effect of CAR-T, and build a project which is dedicated to weakening its effect.  </p>     
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                    <img src="https://static.igem.org/mediawiki/2018/thumb/2/2f/T--NAU-China--hp2.jpg/1200px-T--NAU-China--hp2.jpg" class="hp-photo"/><br/>
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                    <figcaption><center>Seminar for establish our project </figcaption></center> <br/><br/>
  
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<h1>Human Practices</h1>
 
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At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and the work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design and execution.
 
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<p>Next, we conducted interviews scientifically. We brought our idea and our project to principal investigators in Chinese Academy of Sciences, medical researchers and doctors. Taking their suggestions, we corrected and improved our project, changing the application field of our project from weakening cytokine storm to monitoring EFGR targeted cancer. It makes our project more scientific and practical.</p>    
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<p>For more information, please see the <a href="https://2018.igem.org/Human_Practices">Human Practices Hub</a>. There you will find:</p>
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                    <figcaption><center> Interview principal investigators of CAS </figcaption></center> <br/><br/>
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<p>Through human practice, we learned about CAR-T, the latest cancer immunotherapy, and learned in detail about its ins and outs, including its side effects, cytokine storms. We also learned more about EGFR, how it links cancer, and cancer treatments that target it. We also learned about society's perception of cancer and how to conduct investigations scientifically to understand society. </p>
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<li> an <a href="https://2018.igem.org/Human_Practices/Introduction">introduction</a> to Human Practices at iGEM </li>
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<li>tips on <a href="https://2018.igem.org/Human_Practices/How_to_Succeed">how to succeed</a> including explanations of judging criteria and advice about how to conduct and document your Human Practices work</li>
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<li>descriptions of <a href="https://2018.igem.org/Human_Practices/Examples">exemplary work</a> to inspire you</li>
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<li>links to helpful <a href="https://2018.igem.org/Human_Practices/Resources">resources</a></li>
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<li>And more! </li>
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<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
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<p>If your team has gone above and beyond in work related to safety, then you should document this work on your Safety wiki page and provide a description and link on this page. If your team has developed education and public engagement efforts that go beyond a focus on your particular project, and for which would like to nominate your team for the Best Education and Public Engagement Special Prize, you should document this work on your Education and Education wiki page and provide a description and link here. </p>
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<h1> Gold</h1>
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<p>We integrated our human practice into our project.</p>
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<p>First, our project began with human practice. Human practice team brought CAR-T to our team, and we designed our project in order to weaken cytokine storm.  </p>
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<p>Second, our project was revised by human practice. We have changed the application prospect of our project from weakening cytokine storm to monitoring EFGR targeted cancer, by following recommendations from interviewing principal investigators in Chinese Academy of Sciences. The reason why we changed it is that Synnotch cannot be used in the solution environment. EGFR, a kind of protein on the surface of the cell membrane, can be bound with synthetic extracellular recognition domain of Synnotch effectively.</p>
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<p>Third, we brought our project to practitioners in the related fields. We demonstrated how our project can be used in these fields and received feedbacks.</p>
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<p>(More related works have been shown <a href="https://2018.igem.org/Team:NAU-CHINA/Integrated_Human_Practices">in integrated human practice</a>.) </p>
  
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<p>The iGEM judges will review this page to assess whether you have met the Silver and/or Gold medal requirements based on the Integrated Human Practices criteria listed below. If you nominate your team for the <a href="https://2018.igem.org/Judging/Awards">Best Integrated Human Practices Special Prize</a> by filling out the corresponding field in the <a href="https://2018.igem.org/Judging/Judging_Form">judging form</a>, the judges will also review this page to consider your team for that prize.
 
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<h1> Education & Public Engagement</h1>
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<p>Our purpose of benefitting the world by using synthetic biology requires us to spread scientific knowledge to the general public to eliminate their misunderstanding in the field of cancer. We also bear a responsibility to inspire more and more teenagers and students to know about synthetic biology and then understand it deeply.</p>
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<p>(More related works have been shown in our <a href="https://2018.igem.org/Team:NAU-CHINA/Public_Engagement">Education & Public Engagement page</a>. )</p>
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                    <img src="https://static.igem.org/mediawiki/2018/thumb/f/f9/T--NAU-China--hp4.jpg/891px-T--NAU-China--hp4.jpg" class="hp-photo"><br/>
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                    <figcaption><center> Our education & public engagement works </figcaption></center> <br/><br/>
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<h1>iGEMCloud </h1>
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<p>iGEMCloud is a mobile phone software we developed to solve some of iGEM's current problems, with its immediacy, openness and interactivity.</p>
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<p>(See more related information in <a href="https://2018.igem.org/Team:NAU-CHINA/Software">iGEMCloud</a>.)</p>
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<h3>Silver Medal Criterion #3</h3>
 
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<p>Convince the judges you have thought carefully and creatively about whether your work is responsible and good for the world. Document how you have investigated these issues and engaged with your relevant communities, why you chose this approach, and what you have learned. Please note that surveys will not fulfill this criteria unless you follow scientifically valid methods. </p>
 
  
  
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<h3>Gold Medal Criterion #1</h3>
 
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<p>Expand on your silver medal activity by demonstrating how you have integrated the investigated issues into the purpose, design and/or execution of your project. Document how your project has changed based upon your human practices work.
 
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<h3>Best Integrated Human Practices Special Prize</h3>
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<p>To compete for the Best Integrated Human Practices prize, please describe your work on this page and also fill out the description on the judging form. </p>
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<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
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<p>You must also delete the message box on the top of this page to be eligible for this prize.</p>
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Latest revision as of 02:17, 18 October 2018

Template:2018_NAU-CHINA

header
Software

HUMAN PRACTICES

Overview

As a “bigger picture” of iGEM, with the highest ideal to apply synthetic biology to benefit the world, the year-long human practice of our team goes along with our project. Through human practice, on one hand, we establish and improve our project, and apply our project to the real world; on the other hand, we bring scientific knowledge to the general public, educate teenagers and inspire students. Through human practice, we understand the relationship between the world and synthetic biology.

Sliver

To establish an element with the function of analog-to-digital converter, our project can be used not only in EGFR targeted cancer monitoring and treatment, but also in other disease treatment, environmental pollution monitoring, and any other occasions which involve monitoring and “ all or nothing” corresponding.

We thought carefully about what we can do to serve the world when we established our project. Based on plenty of research on the hottest issues, Human practice group of our team locked CAR-T, a kind of cancer immunotherapy. We intend to focus on Cytokine storm, a side effect of CAR-T, and build a project which is dedicated to weakening its effect.


Seminar for establish our project


Next, we conducted interviews scientifically. We brought our idea and our project to principal investigators in Chinese Academy of Sciences, medical researchers and doctors. Taking their suggestions, we corrected and improved our project, changing the application field of our project from weakening cytokine storm to monitoring EFGR targeted cancer. It makes our project more scientific and practical.


Interview principal investigators of CAS


Through human practice, we learned about CAR-T, the latest cancer immunotherapy, and learned in detail about its ins and outs, including its side effects, cytokine storms. We also learned more about EGFR, how it links cancer, and cancer treatments that target it. We also learned about society's perception of cancer and how to conduct investigations scientifically to understand society.

Gold

We integrated our human practice into our project.

First, our project began with human practice. Human practice team brought CAR-T to our team, and we designed our project in order to weaken cytokine storm.

Second, our project was revised by human practice. We have changed the application prospect of our project from weakening cytokine storm to monitoring EFGR targeted cancer, by following recommendations from interviewing principal investigators in Chinese Academy of Sciences. The reason why we changed it is that Synnotch cannot be used in the solution environment. EGFR, a kind of protein on the surface of the cell membrane, can be bound with synthetic extracellular recognition domain of Synnotch effectively.

Third, we brought our project to practitioners in the related fields. We demonstrated how our project can be used in these fields and received feedbacks.

(More related works have been shown in integrated human practice.)

Education & Public Engagement

Our purpose of benefitting the world by using synthetic biology requires us to spread scientific knowledge to the general public to eliminate their misunderstanding in the field of cancer. We also bear a responsibility to inspire more and more teenagers and students to know about synthetic biology and then understand it deeply.

(More related works have been shown in our Education & Public Engagement page. )


Our education & public engagement works


iGEMCloud

iGEMCloud is a mobile phone software we developed to solve some of iGEM's current problems, with its immediacy, openness and interactivity.

(See more related information in iGEMCloud.)

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