Difference between revisions of "Team:CSU CHINA"
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<h1>Description </h1> | <h1>Description </h1> | ||
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| − | + | The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and behavioural processes in mammals. Prokineticin 2 (PK2), a cysteine-rich secreted protein, functions as an output molecule from the SCN circadian clock. PK2 messenger RNA is rhythmically expressed in the SCN, and the phase of PK2 rhythm is responsive to light entrainment. Molecular and genetic studies have revealed that PK2 is a gene that is controlled by a circadian clock (clock-controlled). | |
| + | We are trying to design a mammalian eukaryotic cell line according to the cell population effect produced by the PK2 signaling molecule. The cell strain is supposed to produce a stable and continuous oscillation without the stimulus of any external cause. | ||
</p> | </p> | ||
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Revision as of 18:57, 27 June 2018
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Description
The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and behavioural processes in mammals. Prokineticin 2 (PK2), a cysteine-rich secreted protein, functions as an output molecule from the SCN circadian clock. PK2 messenger RNA is rhythmically expressed in the SCN, and the phase of PK2 rhythm is responsive to light entrainment. Molecular and genetic studies have revealed that PK2 is a gene that is controlled by a circadian clock (clock-controlled). We are trying to design a mammalian eukaryotic cell line according to the cell population effect produced by the PK2 signaling molecule. The cell strain is supposed to produce a stable and continuous oscillation without the stimulus of any external cause.