Team:NAU-CHINA/Collaborations
Xi'an Jiaotong-Liverpool University
statement:
当时他们希望我们完成的是下面叙述的内容，只是后来他们的模型设计有变，此方案可能被他们舍弃。
XJTLU would like to complete a model describing exosome carrying mRNA into the BBB (blood-brain barrier). It is necessary to construct a relationship about the parameters. We assist them in the construction of the third model.
Our main work is to establish a mathematical model that calculates the effective residual amount of mRNA that reaches endothelial cells after t at a certain size. The method is to check the literature that you have found and the other party's literature to understand their model concept, analyze the main factors affecting the remaining amount: secretion loss and degeneration loss, then discuss the rationality of the model.
The overall purpose of their third model is to simulate the following figure. The purpose of simulating this figure is to obtain a range of effective values of mRNA that finally reaches the nerve cells by simulating the process by which the exosomes pass through the blood-brain barrier.
