Team:NAU-CHINA/Application prospects
From Mosfet to Biomosfet: to make the machine biological and biology engineering
Our system can convert the external fluctuation signals into simple 0 and 1 signals to realize the function of analog-to-digital converter. At the same time, as a result of the introduction of recombinases, our system will theoretically be more accurate as a biological switch, with lower leakage, less signal expression affected by the concentration signal of external inducers, and the system threshold can be adjusted by adjusting the types of downstream promoters and recombinases. Combined with the above three characteristics, our system is very suitable for information processing. If we can convert the expression signals into electrical signals through light sensing elements in the future, we can realize the image displayed on our LOGO ——converting biological information into electronic information, make the machine biological and make biology engineering.
By replacing the upstream extracellular domain with EGFR antibody, our system can recognize EGFR with different density on the surface of cell membrane and judge whether the cell is cancerous or not according to the density of EGFR, thus realizing accurate recognition and attack of cancer cells.（this part need write more! This is our mainly background）
In the process of industrial production, by modifying the upstream channel, cells can identify their own products, metabolic wastes or miscellaneous bacteria, etc., and realize automatic adjustment of production according to external conditions or remind workers to deal with corresponding situations.
By replacing the identification object of the upstream system, the measurement of a certain substance can be realized. By adjusting the types of downstream promoters and recombinases, the system threshold can be adjusted.Then the system can not only detect the presence or absence of substances but also dynamically detect the concentration of the detected substances .
If we install our system in two kinds of cells so that they can recognize each other and inhibit each other, then we can realize the function of group sensing, which can keep the number of two kinds of cells fluctuating within a certain range. And this will play a important role in industrial production, material detection and other fields. If the cells are made to emit fluorescence, the periodic brightness changes of fluorescence can be seen through periodic fluctuations in the number of cells, thus realizing the function of repressilator.