Team:NAU-CHINA/Collaborations
XJTLU-CHINA
Xi'an Jiaotong-Liverpool University iGEM team hoped that we completed the following descriptions, but their model design changed later, and this program may be abandoned by them.
XJTLU would like to complete a model describing exosome carrying mRNA into the BBB (blood-brain barrier). It is necessary to construct a relationship about the parameters. We assisted them in the construction of the third model. Our main work is to establish a mathematical model that calculates the effective residual amount of mRNA that reaches endothelial cells after t at a certain size. The method is to check the literature that you have found and the other party's literature to understand their model concept, analyze the main factors affecting the remaining amount: secretion loss and degeneration loss, then discuss the rationality of the model.
The overall purpose of their third model is to simulate the following figure. The purpose of simulating this figure is to obtain a range of effective values of mRNA that finally reaches the nerve cells by simulating the process by which the exosomes pass through the blood-brain barrier.
OUC-China
We have contacted China Ocean University in the early stage to reach a cooperation. We will provide a PDF version of our Synthetic Biology comic book in our campus synthetic biology and iGEM publicity activities, which we will explain on the day of the event.
On September 28, 2018, the iGEM team of Nanjing Agricultural University and the Science Association of the College of Life Sciences jointly organized the iGEM science popularization activities on campus. The whole activity focused on “going to the laboratory – the daily life of the school team” and “going to the competition”. - Themes and Benefits, "Going Close to Dreams - Recruiting Talents" Three themes, using the panels to present synthetic biology knowledge, iGEM competition profiles and team composition, as well as new topics for this year's iGEM team.
The gifts of this event not only have the "transport RNA" keychain designed by our iGEM team, but also the cooperation support of synthetic biology comics designed by OUC. Many students have come to look up and ask.
Peking
Peking University provided our laboratory with the plasmid we needed.
HZNU-China
HZNU-China has designed the OmpA-RGD protein to achieve this goal because of the need to enhance the targeting of engineered Salmonella they use. RGD is a well-studied tumor homing tripeptide that specifically binds to αvβ3 (αvβ3) integrin, which is widely overexpressed on cancer cells. So there is a cell line called MDA-MB-231 that shows the αvβ3 needed for their further targeting and safety experiments. So we helped them contact the channel from the Shanghai Institute of Biochemistry and Cell Biology to get the cell line.