Difference between revisions of "Team:Edinburgh OG/Model"

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<h1 style="text-align: center;"><strong>Modeling PHA biosynthesis</strong></h1>
 
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<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
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<p>Metabolic engineering and synthetic biology in general are powerful areas of research, but they can only realize a quantum leap in breakthroughs when computational models involved in the Design-Build-Test-Learn engineering paradigm are standardized and implemented in the field. As part of our iGEM project, the models developed are motivated by different objectives and approaches in order to inform and be shaped by our endeavors in the lab:</p>
  
 
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Revision as of 05:54, 13 October 2018

PhagED: a molecular toolkit to re-sensitise ESKAPE pathogens

 

 

 

 

 

Modeling PHA biosynthesis

Metabolic engineering and synthetic biology in general are powerful areas of research, but they can only realize a quantum leap in breakthroughs when computational models involved in the Design-Build-Test-Learn engineering paradigm are standardized and implemented in the field. As part of our iGEM project, the models developed are motivated by different objectives and approaches in order to inform and be shaped by our endeavors in the lab:

Dynamic modeling of the PHA biosynthetic pathway for PHBV co-polymer production

Overview 

Gold Medal Criterion #3

Convince the judges that your project's design and/or implementation is based on insight you have gained from modeling. This could be either a new model you develop or the implementation of a model from a previous team. You must thoroughly document your model's contribution to your project on your team's wiki, including assumptions, relevant data, model results, and a clear explanation of your model that anyone can understand.

The model should impact your project design in a meaningful way. Modeling may include, but is not limited to, deterministic, exploratory, molecular dynamic, and stochastic models. Teams may also explore the physical modeling of a single component within a system or utilize mathematical modeling for predicting function of a more complex device.

Please see the 2018 Medals Page for more information.

Best Model Special Prize

To compete for the Best Model prize, please describe your work on this page and also fill out the description on the judging form. Please note you can compete for both the gold medal criterion #3 and the best model prize with this page.

You must also delete the message box on the top of this page to be eligible for the Best Model Prize.

For those interested in the code behind the implementation, please click here to access our GitHub repository!

Inspiration

Here are a few examples from previous teams: