Difference between revisions of "Team:Montpellier/Description"
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| − | <p>To achieve our goal, we want to design a <i>L. jensenii</i> with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules : <a https:// | + | <p>To achieve our goal, we want to design a <i>L. jensenii</i> with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules : <a https://inspirabiotech.com/en/2018/07/28/igem-montpelier-presents-vagineering-the-proposal-of-a-probiotic-contraceptive/</a></p> |
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Revision as of 10:18, 20 August 2018
Description
To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules :
| Name | Type of molecule | Origin |
|---|---|---|
| Nisin | Lantipeptid | Lactococcus lactis |
| Lacticin 3147 | Lantipeptid | Lactococcus lactis |
| Subtilosin A | Sactipeptid | Bacillus subtilis |
| Magainin II | Magainin | Xenopus laevis |
| LL37 | Cathelicidin antimicrobial peptid | Homo sapiens |
| YLP20 | Antibody | Homo sapiens |
| AS16 | Antibody | Homo sapiens |
The chassis
We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.