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<p> The different parts of the project Vagineering </p>
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Revision as of 11:10, 20 August 2018


Description

The different parts of the project Vagineering

To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules : yo

Spermicidal molecules
Name Type of molecule Origin
Nisin Lantipeptid Lactococcus lactis
Lacticin 3147 Lantipeptid Lactococcus lactis
Subtilosin A Sactipeptid Bacillus subtilis
Magainin II Magainin Xenopus laevis
LL37 Cathelicidin antimicrobial peptid Homo sapiens
YLP20 Antibody Homo sapiens
AS16 Antibody Homo sapiens

The chassis

We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.