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Revision as of 09:01, 24 August 2018
Description
The different parts of the Vagineering project
To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules :
Name | Type of molecule | Origin |
---|---|---|
Nisin | Lantipeptid | Lactococcus lactis |
Lacticin 3147 | Lantipeptid | Lactococcus lactis |
Subtilosin A | Sactipeptid | Bacillus subtilis |
Magainin II | Magainin | Xenopus laevis |
LL37 | Cathelicidin antimicrobial peptid | Homo sapiens |
YLP20 | Antibody | Homo sapiens |
AS16 | Antibody | Homo sapiens |
The chassis
We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.