Difference between revisions of "Team:Montpellier/Description"

Line 39: Line 39:
 
   <tr>
 
   <tr>
 
       <td>Nisin</td>
 
       <td>Nisin</td>
      <td>Lantipeptid</td>
 
      <td>Lactococcus lactis</td>
 
  </tr>
 
  <tr>
 
      <td>Lacticin 3147</td>
 
 
       <td>Lantipeptid</td>
 
       <td>Lantipeptid</td>
 
       <td>Lactococcus lactis</td>
 
       <td>Lactococcus lactis</td>
Line 53: Line 48:
 
   </tr>
 
   </tr>
  
  <tr>
 
      <td>Magainin II</td>
 
      <td>Magainin</td>
 
      <td>Xenopus laevis</td>
 
  </tr>
 
 
   <tr>
 
   <tr>
 
       <td>LL37</td>
 
       <td>LL37</td>

Revision as of 09:18, 24 August 2018


Description

The different parts of the Vagineering project

To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules :

Spermicidal molecules
Name Type of molecule Origin
Nisin Lantipeptid Lactococcus lactis
Subtilosin A Sactipeptid Bacillus subtilis
LL37 Cathelicidin antimicrobial peptid Homo sapiens
YLP20 Antibody Homo sapiens
AS16 Antibody Homo sapiens

The chassis

We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.