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Revision as of 10:55, 31 August 2018


Description

The different parts of the Vagineering project

To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules :

Spermicidal molecules
Name Type of molecule Origin
Nisin Lantipeptid Lactococcus lactis
Subtilosin A Sactipeptid Bacillus subtilis
LL37 Cathelicidin antimicrobial peptid Homo sapiens
YLP20 Antibody Homo sapiens
AS16 Antibody Homo sapiens

The chassis

We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.