Team:Montpellier/Description
Description
To achieve our goal, we want to design a L. jensenii with a spermicidal effect which can allow a long term contraception for women. We are focusing on different types of spermidical molecules :
| Name | Type of molecule | Origin |
|---|---|---|
| Nisin | Lantipeptid | Lactococcus lactis |
| Lacticin 3147 | Lantipeptid | Lactococcus lactis |
| Subtilosin A | Sactipeptid | Bacillus subtilis |
| Magainin II | Magainin | Xenopus laevis |
| LL37 | Cathelicidin antimicrobial peptid | Homo sapiens |
| YLP20 | Antibody | Homo sapiens |
| AS16 | Antibody | Homo sapiens |
The chassis
We are going to use two bacteria : Bacillus subtilis and Lactobacillus jensenii, two gram positive bacteria. We choosed B. subtilis because it's a model bacteria for the gram positive. Indeed the final goal is to modify L. jensenii.