Difference between revisions of "Team:Valencia UPV"

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{{Valencia_UPV/stackinterface.css}}
 
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                              Access to Synthetic Biology by the interested layperson is currently hampered by several barriers, including a required background knowledge and availability of expensive and often bulky technological equipment. Printeria, a fully-equipped bioengineering device able to automate the process of printing genetic circuits in bacteria but made as simple and easy to operate as a domestic desktop printer, breaks down these barriers. It uses a digital microfluidic system creating little droplets that can be mixed and moved across predefined electrode paths on a PCB surface. Printeria combines this novel system with Golden Gate Technology, low-cost sensors and electronics, and a user-friendly software application. This way, the user is capable of assembling domesticated DNA parts in a one-step reaction and can control all biotechnological steps, from the assembly of parts and transformation to cell culture, with high accuracy. Printeria opens the door to a world of applications affordable for the general public.
 +
                            </p></div><img alt="image" loop="infinite" src="https://static.igem.org/mediawiki/2018/3/37/T--Valencia_UPV--ImagenHomeNegroDerUPV2018.jpeg" style="
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            </section></div>
  
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<!--------------------------------------------TEXTO------------------------------------------------>
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                                <h4 style="
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padding-bottom: 20px;; font-weight: bold;padding-top: 0px;;">Have you ever thought about breaking down the barriers that prevent people from coming to Synthetic Biology? What if we told you that anyone could be able to program a living being as small as a bacterium? How easy do you think it could be?
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                                <p style="
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padding-top: 7px;"><b>SynBio </b> can be very complex due to the expertise required and the economic cost of the labs. This is why the <b>Valencia UPV team</b> has set a goal: to solve all these difficulties in order to bring Synthetic Biology closer to people.
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                                To face this challenge, what do we propose? We intend to design a fully-equipped bioengineering device: <b>Printeria</b>. It will be capable of modifying bacteria to obtain tangible phenotypes, but made as easy to operate as a home printer. In short, a whole <b>cloning process</b> contained <b>in a single device</b>.
 
  
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But, how does Printeria really work? Printeria includes an extensive collection of promoters, RBS, coding sequences and terminators. Using the <b>Golden Gate Technology</b>, it is capable of assembly these domesticated <b>DNA parts</b> in one-step reaction to obtain different transcriptional units, so that they are expressed in specific bacterial chassis. We achieve this using a digital <b> microfluidic system </b> that is able to create <b>little droplets</b>, which can be controlled across predefined electrode paths on a PCB surface. With this novel system we can mix and move the substrates of the reactions and, definitively, control all biotechnological processes with high accuracy. Anyone who wants to use Printeria will be able to do so through a very <b>intuitive interface</b> that allows the user to select which DNA parts will be assembled. In conclusion, a device that integrates hardware, software and biology.
 
  
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                                Our team is convinced that there is still a lot to be done in the <b>SynBio expansion</b> and we want to continue on this direction. Therefore, we are going to work so that Printeria will have a place in fields as diverse as education, laboratories or bio-art.
 
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                                <p style="font-weight: bold !important;">This is our project. Do you want to join us? </p>
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                                    <div class="col-md-12" style="
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<div style="
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margin-top: -14px;"><img src="https://static.igem.org/mediawiki/2018/5/55/T--Valencia_UPV--EsquemaHomeUPV2018.png" style="
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margin-top: -8em;"><div><a href="https://2018.igem.org/Team:Valencia_UPV/Software"><div style="
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float: left; width: 52%;;"><img src="https://static.igem.org/mediawiki/2018/b/b5/T--Valencia_UPV--EsquemaHomeSoftUPV2018.png" style="
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</div></a></div><div><a href="https://2018.igem.org/Team:Valencia_UPV/Parts"><div style="
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width: 100%;
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background-image: url(https://static.igem.org/mediawiki/2018/9/90/T--Valencia_UPV--GifHomeHardwareUPV2018.gif);"></div><p style="
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Revision as of 13:12, 14 October 2018

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Access to Synthetic Biology by the interested layperson is currently hampered by several barriers, including a required background knowledge and availability of expensive and often bulky technological equipment. Printeria, a fully-equipped bioengineering device able to automate the process of printing genetic circuits in bacteria but made as simple and easy to operate as a domestic desktop printer, breaks down these barriers. It uses a digital microfluidic system creating little droplets that can be mixed and moved across predefined electrode paths on a PCB surface. Printeria combines this novel system with Golden Gate Technology, low-cost sensors and electronics, and a user-friendly software application. This way, the user is capable of assembling domesticated DNA parts in a one-step reaction and can control all biotechnological steps, from the assembly of parts and transformation to cell culture, with high accuracy. Printeria opens the door to a world of applications affordable for the general public.

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CONTACT US igem.upv.2018@gmail.com