Line 162: | Line 162: | ||
<li><p>Provide Printeria with the best way to transform competent bacteria with the highest transformation efficiency rate. | <li><p>Provide Printeria with the best way to transform competent bacteria with the highest transformation efficiency rate. | ||
</p></li> | </p></li> | ||
− | <li><p>Avoid the plate colony screening step in order to eliminate the necessity of the researcher visual check, so easing Printeria automation.</p></li> | + | <li><p>Avoid the plate colony screening step in order to eliminate the necessity of the researcher visual check, so easing Printeria automation.</p></li></ul> |
− | + | <h4>Hardware</h4> | |
+ | <ul> | ||
+ | <li><p>Integrate multiple lab equipment around an automated friendly form. | ||
+ | </p></li> | ||
+ | <li><p>Design an easy way of handling a big variety of input liquids providing a straightforward integration with Printeria. | ||
+ | </p></li> | ||
+ | <li><p>Design an easy to use way of handling a big variety of input liquids with easy integration of the machine. | ||
+ | </p></li> | ||
+ | <li><p>Keep the footprint of the machine as small as possible. | ||
+ | </p></li> | ||
+ | <li><p>Allow for maximum flexibility on the use of the machine. | ||
+ | </p></li> | ||
+ | </ul> | ||
+ | |||
+ | <h4>Software</h4> | ||
+ | <ul> | ||
+ | <li><p>Develop a software that allows the user to control the device. | ||
+ | </p></li> | ||
+ | <li><p>Allow the user to design a transcriptional unit with the software. | ||
+ | |||
+ | </p></li> | ||
+ | <li><p>Allow the user to design multi-genetic constructions with the software.</p></li> | ||
+ | <li><p>Get non-professional users to print basic genetic circuit. | ||
+ | |||
+ | </p></li><li><p>Fill out a “recipe” repository with at least 20 recipes. | ||
+ | </p></li><li><p>Make a user friendly interface to interact with the software. | ||
+ | |||
+ | </p></li><li><p>Control the device’s inventory through the software. | ||
+ | |||
+ | </p></li><li><p>Simulate the bacterial growth and the protein expression. | ||
+ | </p></li> | ||
+ | </ul> | ||
+ | |||
+ | <h4>Modeling</h4> | ||
+ | <ul> | ||
+ | <li><p>Design simple mathematical models based which allows us to simulate the different Printeria genetic circuits. | ||
+ | </p></li> | ||
+ | <li><p>Optimize model parameters to match simulation results to experimental data obtained from Printeria. | ||
+ | |||
+ | </p></li> | ||
+ | <li><p>Characterize the parts of our Part Collection from the optimization results and provide the user with all the information about the Printeria kit. | ||
+ | </p></li> | ||
+ | <li><p>Develop a Simulation Tool that allows the user to visualize a prediction of the results of their experiment before running it in Printeria. | ||
+ | </p></li></ul> | ||
Revision as of 21:48, 14 October 2018
Index
Goals
At the start of the summer, the different members of the Valencia_UPV team set themselves objectives in their respective areas to promote the automation of the cloning process and thus bring synthetic biology closer to the people.
Wet Lab
Create a standardized Golden Gate basic Parts Collection to supply Printeria with the DNA toolkit to assemble composite parts.
Provide Printeria with the best way to transform competent bacteria with the highest transformation efficiency rate.
Avoid the plate colony screening step in order to eliminate the necessity of the researcher visual check, so easing Printeria automation.
Hardware
Integrate multiple lab equipment around an automated friendly form.
Design an easy way of handling a big variety of input liquids providing a straightforward integration with Printeria.
Design an easy to use way of handling a big variety of input liquids with easy integration of the machine.
Keep the footprint of the machine as small as possible.
Allow for maximum flexibility on the use of the machine.
Software
Develop a software that allows the user to control the device.
Allow the user to design a transcriptional unit with the software.
Allow the user to design multi-genetic constructions with the software.
Get non-professional users to print basic genetic circuit.
Fill out a “recipe” repository with at least 20 recipes.
Make a user friendly interface to interact with the software.
Control the device’s inventory through the software.
Simulate the bacterial growth and the protein expression.
Modeling
Design simple mathematical models based which allows us to simulate the different Printeria genetic circuits.
Optimize model parameters to match simulation results to experimental data obtained from Printeria.
Characterize the parts of our Part Collection from the optimization results and provide the user with all the information about the Printeria kit.
Develop a Simulation Tool that allows the user to visualize a prediction of the results of their experiment before running it in Printeria.