Difference between revisions of "Team:TU Darmstadt/Project/Polymers"
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==Polymers== | ==Polymers== | ||
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In order to produce PLGA and PLGC, there are many different ways of polymerization. Given that our polymer is a polyester, there are two possibilities of polymerization. The first one is a polycondensation directly out of the monomers lactic- and glycolic acid by eliminating water molecules. A problem of this method is, that the resulting polymer has lower molecular weights, which diminish the mechanical characteristics. Another possibility is to use an anionic ring opening polymerization. However, it is necessary to dimerize the monomers before using them for such a polymerization, otherwise an anionic ring opening polymerization would not work. The reason why we chose an anionic ring opening polymerization for our project is the fact that such a polymerization causes high molecular weights and is controllable by the amount of initiator used in the set up. | In order to produce PLGA and PLGC, there are many different ways of polymerization. Given that our polymer is a polyester, there are two possibilities of polymerization. The first one is a polycondensation directly out of the monomers lactic- and glycolic acid by eliminating water molecules. A problem of this method is, that the resulting polymer has lower molecular weights, which diminish the mechanical characteristics. Another possibility is to use an anionic ring opening polymerization. However, it is necessary to dimerize the monomers before using them for such a polymerization, otherwise an anionic ring opening polymerization would not work. The reason why we chose an anionic ring opening polymerization for our project is the fact that such a polymerization causes high molecular weights and is controllable by the amount of initiator used in the set up. | ||
The manufactured polymers are than analyzed by gel permeation chromatography (GPC) to determine their molecule weight. | The manufactured polymers are than analyzed by gel permeation chromatography (GPC) to determine their molecule weight. | ||
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===PLGC=== | ===PLGC=== | ||
===Characterization & Analysis=== | ===Characterization & Analysis=== | ||
===Applications=== | ===Applications=== | ||
Revision as of 14:33, 14 October 2018
Polymers
PLGA
In order to produce PLGA and PLGC, there are many different ways of polymerization. Given that our polymer is a polyester, there are two possibilities of polymerization. The first one is a polycondensation directly out of the monomers lactic- and glycolic acid by eliminating water molecules. A problem of this method is, that the resulting polymer has lower molecular weights, which diminish the mechanical characteristics. Another possibility is to use an anionic ring opening polymerization. However, it is necessary to dimerize the monomers before using them for such a polymerization, otherwise an anionic ring opening polymerization would not work. The reason why we chose an anionic ring opening polymerization for our project is the fact that such a polymerization causes high molecular weights and is controllable by the amount of initiator used in the set up. The manufactured polymers are than analyzed by gel permeation chromatography (GPC) to determine their molecule weight.