Team:Valencia UPV/Modeling

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Modeling

Do you think it is possible to mathematically describe a cell? Would you like to know the possibilities that Printeria modeling offers you?

One of the fundamental bases of the Printeria project has undoubtedly been mathematical modeling. Thanks to the development and application of new mathematical models, it is possible to quantify the expression of proteins in cells, and therefore characterize through different experiments the parts designed by Printeria. From the Printeria modeling team, we intend to reach different goals:

  • Design simple mathematical models based on differential equations that describe the biochemical processes of a cell. With them, we can simulate the different genetic circuits that Printeria allows us to build.

  • Develop a Simulation Tool that allows the user to visualize a prediction of the results of their experiment before running it in Printeria.

  • Optimize model parameters to match simulation results to experimental data obtained from Printeria constructions.

  • Characterize the parts of our Part Collection from the optimization results and provide the user with all the information about the Printeria kit.

Although in the development of the project we have dealt with all these aspects, all of them have a single purpose: to understand and describe in a mathematical way the biological processes that take place inside the cell.

Models & Experiments

Characterisation procedures

Simulation Tool

Models & Experiments

Characterisation procedures

Simulation Tool

CONTACT US igem.upv.2018@gmail.com